SCHEMBL6256174

SCHEMBL6256174

CCCCCCCCCCCCCCCC=CC1=NC(CCO)CN1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GLB1 P16278 3/20 0.33
GBA2 Q9HCG7 2/20 0.33
GBA1 P04062 1/20 0.33
CCR5 P51681 4/20 0.32
TNNC1 P63316 1/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7778407 0.86 CCR5 (0.32) CCR5CYP2C19
SCHEMBL11014260 0.86 CCR5 (0.34) CCR5
SCHEMBL7158875 0.82 EPHX2 (0.38) CYP2C19
SCHEMBL9098243 0.82 EPHX2 (0.38) CYP2C19
SCHEMBL872170 0.81 CNR2 (0.35) GLB1GBA2GBA1CYP2C19
SCHEMBL324903 0.77 GBA1 (0.35) GLB1GBA2GBA1
SCHEMBL4631138 0.77 GBA1 (0.35) GLB1GBA2GBA1
SCHEMBL9184068 0.77 GBA1 (0.35) GLB1GBA2GBA1
SCHEMBL1648426 0.77 GBA1 (0.35) GLB1GBA2GBA1
SCHEMBL6161362 0.76 CCR5 (0.36) CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581325-A1 SOLUBILIZED DEFOAMERS FOR CEMENTITIOUS COMPOSITIONS Construction Research & Technology GmbH (DE) 2005-10-05 EP claimed
WO-2004056445-A1 SOLUBILIZED DEFOAMERS FOR CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2004-07-08 WO claimed
US-5405666-A Medical gloves for use on damp or dry skin; having binder, absorbent microparticles and surfactant LRC PRODUCTS LTD. (GB) 1995-04-11 US claimed
US-5395666-A Flexible elastomeric article with enhanced lubricity LRC PRODUCTS LTD. (GB) 1995-03-07 US claimed
EP-0455323-A2 Method of making dipped rubber articles LRC PRODUCTS LIMITED (GB) 1991-11-06 EP claimed
EP-0105613-B1 DIPPED RUBBER ARTICLE LRC PRODUCTS LIMITED (GB) 1988-11-23 EP claimed
US-4575476-A SURGEON'S GLOVES Podell, Howard I. (US) 1986-03-11 US claimed
EP-0105613-A1 Dipped rubber article LRC PRODUCTS LIMITED (GB) 1984-04-18 EP claimed
WO-1984000908-A1 DIPPED RUBBER ARTICLE LRC PRODUCTS (GB) 1984-03-15 WO claimed
CN-106459808-B Friction modifier mixtures providing good friction performance for transmission fluids 路博润公司 2020-10-27 CN disclosed
EP-3161114-B1 MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS LUBRIZOL CORP (US) 2018-06-06 EP disclosed
EP-3161114-A1 MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS The Lubrizol Corporation (US) 2017-05-03 EP disclosed
US-20170096613-A1 MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS THE LUBRIZOL CORPORATION 2017-04-06 US disclosed
WO-2015200592-A1 MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS THE LUBRIZOL CORPORATION (US) 2015-12-30 WO disclosed
WO-1990004626-A2 LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS EXHIBITING IMPROVED DEMULSIBILITY THE LUBRIZOL CORPORATION (US) 1990-05-03 WO disclosed
EP-0105613-B1 DIPPED RUBBER ARTICLE LRC PRODUCTS LIMITED (GB) 1988-11-23 EP disclosed
WO-1988007074-A1 PREPARATION OF SOLUTIONS OF METAL SOAPS IN AMINES MALLINCKRODT, INC. (US) 1988-09-22 WO disclosed
US-4575476-A SURGEON'S GLOVES Podell, Howard I. (US) 1986-03-11 US disclosed
EP-0105613-A1 Dipped rubber article LRC PRODUCTS LIMITED (GB) 1984-04-18 EP disclosed
WO-1984000908-A1 DIPPED RUBBER ARTICLE LRC PRODUCTS (GB) 1984-03-15 WO disclosed