Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391589 | 1.00 | ADRB2 (0.41) | ADRB2MRGPRX4ADRB1PPIACCR5 | |
| SCHEMBL6111245 | 0.96 | ADRB2 (0.47) | ADRB2MRGPRX4ADRB1PPIALMNA | |
| SCHEMBL13589456 | 0.89 | ADRB2 (0.46) | ADRB2ADRB1CCR5LMNAELANE | |
| SCHEMBL4392141 | 0.89 | ADRB2 (0.47) | ADRB2ADRB1CCR5LMNAELANE | |
| SCHEMBL4393381 | 0.89 | ADRB2 (0.47) | ADRB2ADRB1CCR5LMNAELANE | |
| SCHEMBL4387444 | 0.88 | ADRB2 (0.41) | ADRB2ADRB1CCR5LMNAELANE | |
| SCHEMBL4387438 | 0.88 | ADRB2 (0.41) | ADRB2ADRB1CCR5LMNAELANE | |
| SCHEMBL6110678 | 0.87 | ADRB2 (0.42) | ADRB2ADRB1CCR5LMNA | |
| SCHEMBL2452136 | 0.87 | ADRB2 (0.44) | ADRB2MRGPRX4PPIA | |
| SCHEMBL2452137 | 0.87 | ADRB2 (0.44) | ADRB2MRGPRX4PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577291-A1 | Phenylethanolamine derivatives as beta-2 agonists | Pfizer Limited (GB) | 2005-09-21 | — | — | EP | disclosed |