SCHEMBL625651

SCHEMBL625651

CCOC(=O)/C=C\C(=O)OC(=O)/C=C\C(=O)OCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.70
MAPT P10636 5/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.48
SOAT1 P35610 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.44
MDM2 Q00987 1/20 0.44
HSD17B10 Q99714 1/20 0.43
TTR P02766 1/20 0.43
DPP4 P27487 1/20 0.43
ALOX15 P16050 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Maleate SCHEMBL60423 0.92 HCAR2 (0.80) HCAR2MAPTATMNPSR1SOAT1
Diethyl Maleate SCHEMBL2015896 0.92 HCAR2 (0.80) HCAR2MAPTATMNPSR1SOAT1
Diethyl Maleate SCHEMBL27966383 0.92 HCAR2 (0.80) HCAR2MAPTATMNPSR1SOAT1
Diethyl Maleate SCHEMBL2015895 0.92 HCAR2 (0.80) HCAR2MAPTATMNPSR1SOAT1
Diethyl Maleate SCHEMBL42602 0.92 HCAR2 (0.80) HCAR2MAPTATMNPSR1SOAT1
Diethyl Maleate SCHEMBL43033 0.92 HCAR2 (0.80) HCAR2MAPTATMNPSR1SOAT1
SCHEMBL1133860 0.91 HCAR2 (0.87) HCAR2MAPTATMNPSR1SOAT1
SCHEMBL4179973 0.91 HCAR2 (0.59) HCAR2MAPTATMNPSR1SOAT1
SCHEMBL28716204 0.90 HCAR2 (0.64) HCAR2MAPTATMNPSR1SOAT1
Diethyl Maleate SCHEMBL8935022 0.89 HCAR2 (0.76) HCAR2MAPTATMNPSR1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018143-B2 Ionomers of ethylene acid copolymers with enhanced creep resistance DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-25 US claimed
US-11919979-B2 Ionomers of ethylene acid copolymers with enhanced creep resistance DOW GLOBAL TECHNOLOGIES, LLC (US) 2024-03-05 US claimed
CN-117362543-A Crosslinking viscosity-reducing polycarboxylic acid mother solution and preparation method thereof 昆明理工大学 2024-01-09 CN claimed
EP-3762973-B1 PHOTOVOLTAIC MODULE AND ENCAPSULANT COMPOSITION HAVING IMPROVED RESISTANCE TO POTENTIAL INDUCED DEGRADATION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-29 EP claimed
EP-3830187-B1 IONOMERS OF ETHYLENE ACID COPOLYMERS WITH ENHANCED CREEP RESISTANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-02 EP claimed
US-20210380775-A1 POLYAMIDE FOAM PREPARATION PERFORMANCE MATERIALS NA, INC. (US) 2021-12-09 US claimed
EP-3856827-A1 POLYAMIDE FOAM PREPARATION Performance Materials NA, Inc. (US) 2021-08-04 EP claimed
EP-3830187-A2 IONOMERS OF ETHYLENE ACID COPOLYMERS WITH ENHANCED CREEP RESISTANCE Performance Materials NA, Inc. (US) 2021-06-09 EP claimed
US-20210115239-A1 PHOTOVOLTAIC MODULE AND ENCAPSULANT COMPOSITION HAVING IMPROVED RESISTANCE TO POTENTIAL INDUCED DEGRADATION PERFORMANCE MATERIALS NA, INC. (US) 2021-04-22 US claimed
EP-3762973-A1 PHOTOVOLTAIC MODULE AND ENCAPSULANT COMPOSITION HAVING IMPROVED RESISTANCE TO POTENTIAL INDUCED DEGRADATION Performance Materials NA, Inc. (US) 2021-01-13 EP claimed
WO-2020028159-A2 IONOMERS OF ETHYLENE ACID COPOLYMERS WITH ENHANCED CREEP RESISTANCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2020-02-06 WO claimed
CN-108003305-A A kind of synthetic method of polycarboxylate water-reducer 北京砼帮汇科技有限公司 2018-05-08 CN claimed
CN-105331321-A Lignin modified waterborne polyurethane adhesive and preparation method thereof SUZHOU GAIDE FINE MATERIAL CO LTD 2016-02-17 CN claimed
CN-101805258-B Preparation method of novel vegetable oil polyol for polyurethane rigid foam BEIJING KEJU CHEMICAL & NEW MATERIAL CO LTD 2013-03-27 CN claimed
CN-101805258-A Preparation method of novel vegetable oil polyol for polyurethane rigid foam BEIJING KEJU CHEMICAL & NEW MATERIAL CO LTD 2010-08-18 CN claimed
CN-1749292-A Single component polyurethane foam of improved surface toughness and its preparing method HAOHAI CHEMICAL CO LTD SHANGHA (CN) 2006-03-22 CN claimed
US-6797743-B2 Antimicrobial polymer MICHIGAN BIOTECHNOLOGY INSTITUTE 2004-09-28 US claimed
EP-0455412-B1 Hot melt adhesive compositions DU PONT (US) 1995-02-22 EP claimed
US-5137974-A Ethylene copolymer grafted with lactam oligomer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-11 US claimed
EP-0455412-A2 Hot melt adhesive compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-06 EP claimed