SCHEMBL6256575

SCHEMBL6256575

CC(C)(C)C#C[Mg]Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6095539 0.75
SCHEMBL11169286 0.67
SCHEMBL4119428 0.64
SCHEMBL16967 0.60
SCHEMBL6059441 0.60
SCHEMBL2161853 0.57
SCHEMBL1467334 0.55
SCHEMBL2508494 0.53
SCHEMBL18984686 0.53
SCHEMBL25277803 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10221198-B2 Preparation and medical use of triazenes ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2019-03-05 US disclosed
US-20170158714-A1 Preparation and Medical Use of Triazenes ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2017-06-08 US disclosed
WO-2015197096-A1 PREPARATION AND MEDICAL USE OF TRIAZENES ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2015-12-30 WO disclosed
WO-2013123444-A1 SULFONYL COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN AMGEN INC. (US) 2013-08-22 WO disclosed
WO-2005058794-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TERBINAFINE INTERMEDIATE NATCO PHARMA LIMITED (IN) 2005-06-30 WO disclosed