SCHEMBL625681

SCHEMBL625681

CCCCCC[Si](CCCN)(CCCCCC)CCCCCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.60
TSHR P16473 2/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
ALDH1A1 P00352 1/20 0.60
EPHX1 P07099 1/20 0.60
THRB P10828 1/20 0.42
HTR2A P28223 1/20 0.37
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24075496 0.92 DNM1 (0.65) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL20582506 0.89 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL10401825 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL10841725 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL2124312 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL7849811 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL16209877 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL10841183 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1329750 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL2119967 0.86 TSHR (0.57) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012019256-A1 SILICONE ELASTOMER-BASED COMPOSITIONS, ARTICLES AND METHOD FOR PROTECTION AGAINST CORROSION PETROENGE PETRÓLEO ENGENHARIA LTDA (BR) 2012-02-16 WO disclosed