Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252744 | 0.82 | CYP1A2 (0.43) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6255985 | 0.80 | CYP1A2 (0.48) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6257775 | 0.79 | CYP2A6 (0.43) | CYP1A2 | |
| SCHEMBL6253656 | 0.79 | CYP2A6 (0.31) | — | |
| SCHEMBL6257782 | 0.78 | NPC1 (0.40) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8168452 | 0.77 | NPC1 (0.41) | CYP1A2NPC1RAB9AHTR3A | |
| SCHEMBL6256247 | 0.77 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL6256314 | 0.77 | CYP1A2 (0.44) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6253891 | 0.77 | CYP1A2 (0.44) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6253395 | 0.76 | CYP1A2 (0.43) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |