SCHEMBL6256983

SCHEMBL6256983

Cc1cc(N)ccc1NCCCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
NQO2 P16083 4/20 0.47
RAD52 P43351 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
ENPP1 P22413 2/20 0.42
NR4A2 P43354 1/20 0.41
GART P22102 1/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4825292 0.94 NQO2 (0.51) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL4828295 0.91 MAPT (0.51) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL4826787 0.91 MAPT (0.51) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL4829925 0.85 MAPT (0.54) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL12943222 0.84 KMT2A (0.51) MAPTKDM4EALDH1A1GAAKMT2A
SCHEMBL6369704 0.84 NQO2 (0.47) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL4826649 0.83 MAPT (0.55) CYP1A2MAPTCYP2C9CYP2C19NQO2
Hydrochloric Acid SCHEMBL4955142 0.82 NQO2 (0.46) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL6369919 0.82 NQO2 (0.54) CYP1A2MAPTCYP2C9CYP2C19NQO2
SCHEMBL6377800 0.82 NQO2 (0.54) CYP1A2MAPTCYP2C9CYP2C19NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1580186-A1 Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses L'OREAL (FR) 2005-09-28 EP claimed
EP-1580186-A1 Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses L'OREAL (FR) 2005-09-28 EP disclosed