Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826787 | 1.00 | MAPT (0.51) | MAPTCYP1A2CYP2C9CYP2C19APEX1 | |
| SCHEMBL6256983 | 0.91 | CYP1A2 (0.49) | MAPTCYP1A2CYP2C9CYP2C19APEX1 | |
| SCHEMBL4825292 | 0.88 | NQO2 (0.51) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL9404784 | 0.87 | ALDH1A1 (0.45) | MAPTCYP1A2CYP2C9CYP2C19APEX1 | |
| SCHEMBL4827101 | 0.84 | MAPT (0.47) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL4824607 | 0.82 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL5930664 | 0.80 | MAPT (0.42) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL29392615 | 0.80 | CYP2C19 (0.45) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL33660 | 0.80 | CYP2C19 (0.45) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL11330558 | 0.79 | MAPT (0.47) | MAPTCYP1A2CYP2C9CYP2C19RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | claimed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| EP-1580186-A1 | Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1580186-A1 | Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | KRT18, CDC73, JUP | MAPT 1947/4885CYP1A2 1398/4885CYP2C9 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.