SCHEMBL625699

SCHEMBL625699

C=C(C(=O)O)c1ccc2ccccc2c1.CC(=Cc1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.49
KDM4E B2RXH2 2/20 0.48
HPGD P15428 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
EGFR P00533 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
PKM P14618 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
JAK1 P23458 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP1B1 Q16678 1/20 0.47
DHODH Q02127 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122093 0.87 AKR1C3 (0.63) AKR1C3KDM4EALDH1A1DHODHPTPN1
SCHEMBL29966982 0.87 AKR1C3 (0.63) AKR1C3KDM4EALDH1A1DHODHPTPN1
SCHEMBL51774 0.87 AKR1C3 (0.63) AKR1C3KDM4EALDH1A1DHODHPTPN1
Hydrochloric Acid SCHEMBL27571578 0.85 AKR1C3 (0.61) AKR1C3KDM4EALDH1A1DHODHPTPN1
Hydrochloric Acid SCHEMBL6780341 0.85 AKR1C3 (0.61) AKR1C3KDM4EALDH1A1DHODHPTPN1
SCHEMBL27643098 0.83 CYP3A4 (0.47) AKR1C3KDM4EHPGDSMN1; SMN2MEN1
SCHEMBL1995939 0.82 AKR1C3 (0.61) AKR1C3KDM4EALDH1A1DHODHPTPN1
SCHEMBL124455 0.82 KDM4E (0.61) KDM4EHPGDSMN1; SMN2MEN1ALDH1A1
SCHEMBL625697 0.82 AKR1C2 (0.47) AKR1C3KDM4ECYP3A4DHODHPTPN1
SCHEMBL8746638 0.81 AKR1C3 (0.61) AKR1C3DHODHESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2380775-B1 OPTICALLY PERMEABLE, DEEP DRAWABLE ELECTRODE AND FLAT ELEMENT COMPRISING SAME FOR EL FILMS/LAMPS TESA SE (DE) 2016-11-23 EP disclosed
EP-1882707-B1 bimodal acrylate adhesive mass for gluing low energy and rough surfaces TESA SE (DE) 2016-05-18 EP disclosed
WO-2012020009-A1 LIGHTING MEANS WHICH CAN IN PARTICULAR BE THERMOFORMED TESA SE (DE) 2012-02-16 WO disclosed
EP-2380775-A1 Optically permeable, deep drawable electrode and flat element comprising same for EL films/lamps tesa SE (DE) 2011-10-26 EP disclosed
EP-2001969-B1 ELECTROLUMINESCENT ADHESIVE MASSES TESA SE (DE) 2011-08-03 EP disclosed
EP-2334516-A2 EMBOSSABLE LICENSE PLATE TESA SE (DE) 2011-06-22 EP disclosed
WO-2010037673-A2 EMBOSSABLE LICENSE PLATE TESA SE (DE) 2010-04-08 WO disclosed
WO-2010037712-A2 EMBOSSABLE LICENSE PLATE TESA SE (DE) 2010-04-08 WO disclosed
EP-2168816-A1 Embossable licence plate Sauer, Arno Martin (DE) 2010-03-31 EP disclosed
EP-2001969-A1 ELECTROLUMINESCENT ADHESIVE MASSES Tesa AG (DE) 2008-12-17 EP disclosed
EP-1882707-A1 bimodal acrylate adhesive mass for gluing low energy and rough surfaces Tesa AG (DE) 2008-01-30 EP disclosed
WO-2007107591-A1 ELECTROLUMINESCENT ADHESIVE MASSES TESA AG (DE) 2007-09-27 WO disclosed