Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 18/20 | 1.00 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.67 |
| ▸ | MICA | Q29983 | 2/20 | 0.67 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257358 | 1.00 | MTTP (1.00) | MTTPKLRK1MICARAET1L | |
| SCHEMBL6254466 | 0.91 | MTTP (1.00) | MTTPKLRK1MICARAET1L | |
| SCHEMBL6254470 | 0.91 | MTTP (1.00) | MTTPKLRK1MICARAET1L | |
| SCHEMBL6805734 | 0.85 | MTTP (1.00) | MTTP | |
| SCHEMBL6805732 | 0.85 | MTTP (1.00) | MTTP | |
| SCHEMBL6256963 | 0.80 | MTTP (0.72) | MTTP | |
| SCHEMBL6266170 | 0.75 | MTTP (0.66) | MTTP | |
| SCHEMBL15556509 | 0.75 | MTTP (0.66) | MTTP | |
| SCHEMBL7608025 | 0.74 | MTTP (0.60) | MTTPKLRK1MICARAET1L | |
| SCHEMBL14027951 | 0.73 | MTTP (0.57) | MTTPKLRK1MICARAET1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132745-A1 | Microsomal triglyceride transfer protein inhibitor | PFIZER INC | 2004-07-08 | — | — | US | claimed |
| EP-1578725-A1 | MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004056777-A1 | MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2004-07-08 | — | — | WO | disclosed |
| US-20040132745-A1 | Microsomal triglyceride transfer protein inhibitor | PFIZER INC | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132745-A1 | Microsomal triglyceride transfer protein inhibitor | MTTP, CETP, APOB | MTTP 1/4885KLRK1 3508/4885MICA 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.