Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725593 | 0.79 | TSHR (0.42) | TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL6257885 | 0.78 | HSD17B10 (0.33) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4660178 | 0.75 | CA2 (0.42) | TSHRENPP3ENPP1ALDH1A1 | |
| SCHEMBL23203437 | 0.73 | TSHR (0.39) | TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL4662679 | 0.72 | ERN1 (0.32) | ENPP3ENPP1ALDH1A1 | |
| SCHEMBL30941591 | 0.71 | TSHR (0.57) | TSHRCYP1A2ALDH1A1LMNA | |
| SCHEMBL13485920 | 0.71 | TSHR (0.57) | TSHRCYP1A2ALDH1A1LMNA | |
| SCHEMBL501178 | 0.69 | CYP1A2 (0.50) | TSHRCYP1A2ALDH1A1 | |
| SCHEMBL3381848 | 0.69 | PDPK1 (0.34) | ENPP3ENPP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18290655 | 0.67 | CYP1A2 (0.33) | CYP1A2METAP2LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019207-A1 | FUNGICIDAL PYRIMIDINE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2005-03-03 | — | — | WO | disclosed |
| US-20050038041-A1 | Fungicidal pyrimidine derivatives | NIPPON SODA CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-6818631-B1 | 4-FLUOROALKYL SUBSTITUENT; AGRICULTURE, HORTICULTURE; PLANT DISEASE CONTROL | NIPPON SODA CO. LTD. (JP) | 2004-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038041-A1 | Fungicidal pyrimidine derivatives | CBR3, CBR1, TH | TSHR 64/4885ENPP3 2016/4885ENPP1 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.