Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403848 | 0.76 | CHRNA7 (0.53) | CHRNA7LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11504799 | 0.75 | MEN1 (0.54) | KCNK3LMNAMEN1KMT2AKCNH2 | |
| SCHEMBL11673632 | 0.74 | EPHX1 (0.56) | LMNAMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL30300553 | 0.73 | MEN1 (0.62) | LMNAMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7438921 | 0.69 | TAS1R3 (0.59) | — | |
| SCHEMBL7438929 | 0.69 | TAS1R3 (0.59) | — | |
| SCHEMBL1232491 | 0.69 | MAPT (0.58) | LMNAMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7438039 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7432770 | 0.68 | TAS1R3 (0.57) | — | |
| Hydrochloric Acid SCHEMBL7432766 | 0.68 | TAS1R3 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025498-A2 | SUBSTITUTED ACETANILIDES AND BENZAMIDES FOR THE TREATMENT OF ASTHMA AND PULMONARY INFLAMMATION | CORUS PHARMA (US) | 2005-03-24 | — | — | WO | disclosed |