SCHEMBL6257967

SCHEMBL6257967

C=C(CCC=CN)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRM1 Q13255 1/20 0.35
GRM2 Q14416 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2054203 0.79 ALOX15 (0.37) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL700123 0.79 ALOX15 (0.37) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL2120851 0.79 ALOX15 (0.37) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL1790763 0.77 ALOX15 (0.35) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL15609460 0.77 ALOX15 (0.35) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL1791045 0.77 ALOX15 (0.35) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL6944776 0.77 TSHR (0.41) GRIK1GRIK2GRM1GRM2ALOX15
SCHEMBL45774 0.76
SCHEMBL23754437 0.76 PPARG (0.36) ALOX15HSD17B10TET2
SCHEMBL11224200 0.76 TDP1 (0.35) GRIK1GRIK2GRM1GRM2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1131057-B1 CUSHIONING WAX BEADS FOR MAKING SOLID SHAPED ARTICLES UNIV GENT (BE) 2005-04-20 EP claimed
EP-0474452-B1 Thermal transfer dye image receiving sheet NEW OJI PAPER CO LTD (JP) 1995-07-12 EP claimed
US-11786476-B2 Oral dosage form UNIVERSITEIT GENT (BE) 2023-10-17 US disclosed
US-20210353548-A1 ORAL DOSAGE FORM UNIVERSITEIT GENT (BE) 2021-11-18 US disclosed
EP-3892263-A1 ORAL DOSAGE FORM Universiteit Gent (BE) 2021-10-13 EP disclosed
US-11065207-B2 Oral dosage form UNIVERSITEIT GENT (BE) 2021-07-20 US disclosed
EP-3432865-B1 ORAL DOSAGE FORM UNIV GENT (BE) 2021-05-19 EP disclosed
US-10966928-B2 Oral dosage form UNIVERSITEIT GENT (BE) 2021-04-06 US disclosed
US-20200297647-A1 ORAL DOSAGE FORM UNIVERSITEIT GENT (BE) 2020-09-24 US disclosed
US-20200214983-A1 ORAL DOSAGE FORM UNIVERSITEIT GENT (BE) 2020-07-09 US disclosed
EP-3432865-A1 ORAL DOSAGE FORM Universiteit Gent (BE) 2019-01-30 EP disclosed
WO-2017162852-A1 ORAL DOSAGE FORM UNIVERSITEIT GENT (BE) 2017-09-28 WO disclosed
EP-0894780-B1 Use of radiation-curable compositions for coating mineral bodies BASF AG (DE) 2003-11-26 EP disclosed
WO-2002017877-A2 CONTROLLED RELEASE PHARMACEUTICAL PELLET COMPOSITIONS FOR REDUCING SIDE EFFECTS OF DRUGS UNIVERSITEIT GENT (BE) 2002-03-07 WO disclosed
EP-0894780-A1 Use of radiation-curable compositions for coating mineral bodies BASF AKTIENGESELLSCHAFT (DE) 1999-02-03 EP disclosed