SCHEMBL6258041

SCHEMBL6258041

CN(CC(F)(F)F)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
NR1H2 P55055 3/20 0.42
NR1H3 Q13133 2/20 0.42
AR P10275 1/20 0.40
NR1I2 O75469 6/20 0.38
RORC P51449 2/20 0.38
RORA P35398 1/20 0.38
RORB Q92753 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TAAR1 Q96RJ0 2/20 0.38
POLQ O75417 1/20 0.38
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28131828 0.83 NR1H3 (0.44) CA12CA2CA9NR1H2NR1H3
SCHEMBL21021291 0.80 AR (0.42) NR1H2NR1H3ARNR1I2RORC
SCHEMBL9770427 0.79 NR1H3 (0.41) CA12CA2CA9NR1H2NR1H3
SCHEMBL10159871 0.79 CA12 (0.44) CA12CA2CA9NR1H2NR1H3
SCHEMBL24865607 0.78 ALDH1A1 (0.48) CA12CA2CA9NR1H2NR1H3
SCHEMBL23977864 0.78 AR (0.41) ARMEN1HTTKMT2A
SCHEMBL10235386 0.77 AR (0.40) NR1H2NR1H3ARMEN1HTT
SCHEMBL10504615 0.76 NR1H2 (0.50) NR1H2NR1H3ARNR1I2RORC
SCHEMBL11556871 0.76 MEN1 (0.41) CA12CA2CA9NR1H2NR1H3
SCHEMBL6699279 0.76 TAAR1 (0.45) CA12CA2CA9MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004528205-A 2004-09-16 JP claimed
EP-1389225-A2 METHOD FOR BONDING A FLUOROPOLYMER TO A SUBSTRATE AND COMPOSITE ARTICLE RESULTING THEREFROM 3M Innovative Properties Company (US) 2004-02-18 EP claimed
US-20030077454-A1 Fluoropolymer bonding composition and method 3M INNOVATIVE PROPERTIES COMPANY 2003-04-24 US claimed
WO-2002094914-A2 METHOD FOR BONDING A FLUOROPOLYMER TO A SUBSTRATE AND COMPOSITE ARTICLE RESULTING THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-28 WO claimed
EP-1578849-A1 METHOD FOR MODIFYING THE SURFACE OF A POLYMERIC SUBSTRATE 3M Innovative Properties Company (US) 2005-09-28 EP disclosed
WO-2004060983-A1 METHOD FOR MODIFYING THE SURFACE OF A POLYMERIC SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-07-22 WO disclosed
US-20040126708-A1 Digitally applying a photoreactive material comprising photochemical electron donor exposing to actinic radiation 3M INNOVATIVE PROPERTIES COMPANY 2004-07-01 US disclosed
EP-1389225-A2 METHOD FOR BONDING A FLUOROPOLYMER TO A SUBSTRATE AND COMPOSITE ARTICLE RESULTING THEREFROM 3M Innovative Properties Company (US) 2004-02-18 EP disclosed
US-6685793-B2 PHOTOPOLYMERIZATION; EXPOSURE TO ACTINIC, ULTRAVIOLET RADIATION 3M INNOVATIVE PROPERTIES COMPANY 2004-02-03 US disclosed
US-20030077454-A1 Fluoropolymer bonding composition and method 3M INNOVATIVE PROPERTIES COMPANY 2003-04-24 US disclosed
WO-2002094914-A2 METHOD FOR BONDING A FLUOROPOLYMER TO A SUBSTRATE AND COMPOSITE ARTICLE RESULTING THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-28 WO disclosed
EP-0244399-B1 NOVEL PHENAZINE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-30 EP disclosed