Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261071 | 0.91 | FFAR1 (0.50) | PPARAPPARGS1PR1S1PR3S1PR5 | |
| SCHEMBL6263977 | 0.88 | S1PR1 (0.46) | PPARAPPARDKMT2AITGB3ITGA2B | |
| SCHEMBL6258194 | 0.88 | S1PR1 (0.53) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6242802 | 0.87 | PPARD (0.41) | PPARAPPARDCA12CA1CA2 | |
| SCHEMBL6261341 | 0.87 | S1PR1 (0.55) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6236920 | 0.87 | S1PR1 (0.55) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6241196 | 0.87 | S1PR1 (0.55) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6257363 | 0.87 | S1PR1 (0.55) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6257966 | 0.83 | S1PR1 (0.51) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6241770 | 0.83 | S1PR1 (0.51) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |