SCHEMBL625822

SCHEMBL625822

CC(=NOC(=O)c1ccccc1)C(=O)C(=O)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
MAPT P10636 5/20 0.47
CDK5 Q00535 3/20 0.47
CDK5R1 Q15078 3/20 0.47
PKM P14618 3/20 0.47
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 6/20 0.44
RAB9A P51151 6/20 0.44
TNF P01375 1/20 0.43
KLF5 Q13887 1/20 0.43
NOD1 Q9Y239 1/20 0.43
MITF O75030 1/20 0.41
RBBP9 O75884 1/20 0.40
LMNA P02545 1/20 0.40
CTSK P43235 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CASP3 P42574 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92109 0.92 KMT2A (0.55) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL13006676 0.92 KMT2A (0.55) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL9967316 0.92 KMT2A (0.55) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL19795426 0.85 KMT2A (0.65) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL16279024 0.85 ALDH1A1 (0.51) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL91995 0.85 ALDH1A1 (0.51) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL19795455 0.83 MAPT (0.60) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL19795449 0.83 MAPT (0.64) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL91920 0.82 ALDH1A1 (0.46) ALDH1A1HPGDSMN1; SMN2MAPTCDK5
SCHEMBL19795456 0.81 KMT2A (0.47) ALDH1A1HPGDSMN1; SMN2MAPTCDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020715-A1 BLUE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-02-16 WO disclosed