SCHEMBL6258317

SCHEMBL6258317

Cc1cnc([C@H](C)NC(=O)OC(C)(C)C)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.42
TRPA1 O75762 1/20 0.41
TSHR P16473 3/20 0.41
HSD17B10 Q99714 2/20 0.41
SSTR3 P32745 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CYP2D6 P10635 1/20 0.38
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
ABCB1 P08183 1/20 0.36
AAK1 Q2M2I8 3/20 0.36
GLA P06280 1/20 0.36
EPHX2 P34913 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6258324 1.00 KMT2A (0.42) KMT2ATRPA1TSHRHSD17B10SSTR3
SCHEMBL27979022 0.82 MMP2 (0.40) KMT2ATRPA1TSHRHSD17B10SSTR3
SCHEMBL14738789 0.82 MMP2 (0.40) KMT2ATRPA1TSHRHSD17B10SSTR3
SCHEMBL14738416 0.82 KMT2A (0.40) KMT2ATRPA1TSHRHSD17B10SSTR3
SCHEMBL14738417 0.82 KMT2A (0.40) KMT2ATRPA1TSHRHSD17B10SSTR3
Hydrochloric Acid SCHEMBL14738248 0.81 MMP2 (0.40) KMT2ATRPA1TSHRHSD17B10SSTR3
Hydrochloric Acid SCHEMBL27978859 0.81 MMP2 (0.40) KMT2ATRPA1TSHRHSD17B10SSTR3
SCHEMBL18481909 0.79 SSTR3 (0.60) SSTR3MAPTATM
SCHEMBL15710994 0.79 SSTR3 (0.46) KMT2ATRPA1TSHRHSD17B10SSTR3
SCHEMBL12175104 0.78 SSTR3 (0.45) KMT2ATRPA1TSHRHSD17B10SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005000309-A2 CHEMICAL COMPOUNDS IONIX PHARMACEUTICALS LIMITED (GB) 2005-01-06 WO disclosed