Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.63 |
| ▸ | RGS12 | O14924 | 1/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SYK | P43405 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL28227462 | 0.92 | EGFR (0.55) | EGFRALDH1A1NOX4RGS12LCK | |
| SCHEMBL6260824 | 0.88 | EGFR (0.52) | EGFRALDH1A1NOX4RGS12LCK | |
| SCHEMBL31060627 | 0.88 | EGFR (0.52) | EGFRALDH1A1NOX4RGS12LCK | |
| SCHEMBL6259074 | 0.85 | EGFR (0.66) | EGFRNOX4HSP90AA1 | |
| SCHEMBL11510342 | 0.81 | CA12 (0.61) | EGFRALDH1A1NOX4RGS12LCK | |
| SCHEMBL9567555 | 0.79 | HPGD (0.63) | ALDH1A1MAPTHPGDHSD17B10POLB | |
| SCHEMBL413096 | 0.78 | EGFR (0.58) | EGFRALDH1A1NOX4RGS12LCK | |
| SCHEMBL4730865 | 0.78 | CDC7 (0.65) | EGFRALDH1A1MAPTHPGDHSD17B10 | |
| Lavendustin C SCHEMBL30569227 | 0.78 | EGFR (1.00) | EGFRALDH1A1NOX4RGS12LCK | |
| Lavendustin C SCHEMBL1821516 | 0.78 | EGFR (1.00) | EGFRALDH1A1NOX4RGS12LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005065074-A2 | PROTECTION OF TISSUES AND CELLS FROM CYTOTOXIC EFFECTS OF IONIZING RADIATION BY ABL INHIBITORS | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2005-07-21 | — | — | WO | claimed |