Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512440 | 0.86 | CA12 (0.61) | CA12CA2CA9EGFRMAPT | |
| SCHEMBL7157513 | 0.83 | CA12 (0.58) | CA12CA2CA9EGFRMAPT | |
| SCHEMBL10782516 | 0.83 | CA12 (0.88) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL4403985 | 0.82 | EGFR (0.53) | CA12CA2CA9EGFRMAPT | |
| Hydrochloric Acid SCHEMBL28825273 | 0.81 | CA12 (0.56) | CA12CA2CA9EGFRMAPT | |
| SCHEMBL6260824 | 0.81 | EGFR (0.52) | CA12CA2CA9EGFRMAPT | |
| SCHEMBL6258501 | 0.81 | EGFR (0.63) | EGFRMAPTALDH1A1RGS12LCK | |
| SCHEMBL31060627 | 0.81 | EGFR (0.52) | CA12CA2CA9EGFRMAPT | |
| SCHEMBL11981619 | 0.80 | EGFR (0.79) | EGFRMAPTALDH1A1RGS12LCK | |
| SCHEMBL5713542 | 0.79 | EGFR (0.53) | CA12CA2CA9EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |