Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 18/20 | 0.44 |
| ▸ | EGFR | P00533 | 16/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232747 | 0.84 | ERBB2 (0.48) | ERBB2EGFRERBB4MEN1RGS12 | |
| SCHEMBL6485315 | 0.75 | ERBB2 (0.61) | ERBB2EGFRERBB4MEN1RGS12 | |
| SCHEMBL6493385 | 0.73 | ERBB2 (0.49) | ERBB2EGFRERBB4MEN1RGS12 | |
| SCHEMBL6493384 | 0.73 | ERBB2 (0.49) | ERBB2EGFRERBB4MEN1RGS12 | |
| Hydrochloric Acid SCHEMBL6827053 | 0.72 | ERBB2 (0.64) | ERBB2EGFRERBB4MEN1RGS12 | |
| SCHEMBL6237787 | 0.72 | EGFR (0.47) | ERBB2EGFRERBB4 | |
| SCHEMBL6826915 | 0.72 | ERBB2 (0.52) | ERBB2EGFRERBB4MEN1RGS12 | |
| SCHEMBL6237155 | 0.72 | ERBB2 (0.57) | ERBB2EGFRERBB4MEN1RGS12 | |
| SCHEMBL6767931 | 0.72 | ERBB2 (0.79) | ERBB2EGFRERBB4MEN1RGS12 | |
| Hydrochloric Acid SCHEMBL6768338 | 0.71 | ERBB2 (0.78) | ERBB2EGFRERBB4MEN1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |