Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232747 | 0.87 | ERBB2 (0.48) | EGFRERBB2ERBB4 | |
| SCHEMBL6258587 | 0.72 | ERBB2 (0.44) | EGFRERBB2ERBB4 | |
| SCHEMBL27730502 | 0.70 | ERBB2 (0.48) | EGFRERBB2ERBB4 | |
| SCHEMBL6827006 | 0.69 | ERBB2 (0.59) | EGFRERBB2ERBB4 | |
| SCHEMBL3609780 | 0.69 | ERBB2 (0.52) | EGFRERBB2ERBB4 | |
| SCHEMBL6255788 | 0.69 | EGFR (0.41) | EGFRERBB2PIP4K2A | |
| Hydrochloric Acid SCHEMBL3508230 | 0.69 | ERBB2 (0.46) | EGFRERBB2ERBB4 | |
| SCHEMBL6235385 | 0.65 | EGFR (0.43) | EGFRERBB2ERBB4 | |
| SCHEMBL4032512 | 0.65 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL6238390 | 0.65 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |