Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260692 | 0.93 | RORA (0.43) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL1715037 | 0.85 | RORA (0.44) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL1715514 | 0.80 | RORA (0.46) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL1939226 | 0.80 | PIK3CG (0.56) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL12461333 | 0.80 | RORA (0.49) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL12201045 | 0.77 | RORA (0.51) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL1939916 | 0.76 | RORA (0.49) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL12203600 | 0.76 | RORA (0.49) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL12203598 | 0.76 | RORA (0.51) | RORARORCRORBPIK3CDPIK3CG | |
| SCHEMBL6101006 | 0.76 | RORA (0.50) | RORARORCRORBPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |