Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC34A1 | Q06495 | 5/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257302 | 0.89 | PTGIR (0.49) | PTGIRNPBWR1L3MBTL1SLC34A1AXL | |
| SCHEMBL6256148 | 0.81 | MEN1 (0.43) | NPBWR1PSMB5KDM4EALDH1A1HPGD | |
| SCHEMBL6254280 | 0.81 | PTGIR (0.51) | PTGIRL3MBTL1SLC34A1AXLTYRO3 | |
| SCHEMBL6258726 | 0.81 | PTGIR (0.53) | PTGIRNPBWR1L3MBTL1SLC34A1AXL | |
| SCHEMBL6254733 | 0.80 | PTGIR (0.50) | PTGIRNPBWR1L3MBTL1SLC34A1AXL | |
| SCHEMBL6260118 | 0.78 | PTGIR (0.48) | PTGIRNPBWR1L3MBTL1SLC34A1AXL | |
| SCHEMBL6254804 | 0.78 | POLB (0.51) | PTGIRL3MBTL1SLC34A1SRCKCNH2 | |
| SCHEMBL6254702 | 0.77 | PTGIR (0.47) | PTGIRNPBWR1L3MBTL1SLC34A1PSMB5 | |
| SCHEMBL6255253 | 0.76 | PTGIR (0.46) | PTGIRNPBWR1L3MBTL1AXLTYRO3 | |
| SCHEMBL6257567 | 0.76 | PTGIR (0.46) | PTGIRNPBWR1L3MBTL1SLC34A1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156039-B1 | PYRIDAZIN-3-ONE DERIVATIVES AND MEDICINES CONTAINING THE SAME | KOWA CO (JP) | 2005-10-05 | — | — | EP | disclosed |
| US-6680316-B1 | INTERLEUKIN INHIBITORS; AUTOIMMUNE, RHEUMATIC, AND GASTROINTESTINAL DISORDERS; OSTEOPOROSIS; ANTIINFLAMMATORY, ANTIISCHEMIC, AND ANTIARTHRITIC AGENTS | KOWA CO., LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| EP-1156039-A1 | PYRIDAZIN-3-ONE DERIVATIVES AND MEDICINES CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |