SCHEMBL6258757

SCHEMBL6258757

NCN1C(=O)C(=O)c2ccccc21

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES1 P23141 8/20 0.71
BCHE P06276 3/20 0.71
TGM2 P21980 1/20 0.71
ALDH1A1 P00352 6/20 0.68
ALDH3A1 P30838 6/20 0.68
ALDH2 P05091 4/20 0.68
CHRM1 P11229 2/20 0.68
PARK7 Q99497 1/20 0.64
MAOA P21397 1/20 0.61
MAOB P27338 1/20 0.61
PKM P14618 1/20 0.60
ACHE P22303 1/20 0.59
RCE1 Q9Y256 1/20 0.58
CES2 O00748 1/20 0.57
CHRM5 P08912 1/20 0.56
CHRM3 P20309 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CDC25A P30304 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9728197 0.85 CES1 (0.79) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL19924204 0.83 CES1 (1.00) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL2087729 0.81 ALDH1A1 (1.00) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL5999219 0.81 CES1 (0.79) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL29506660 0.81 ALDH1A1 (1.00) CES1BCHETGM2ALDH1A1ALDH3A1
Hydrochloric Acid SCHEMBL9247204 0.80 CES1 (0.71) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL25119569 0.80 CES1 (0.85) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL1426402 0.80 CES1 (0.71) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL5114051 0.80 CES1 (0.71) CES1BCHETGM2ALDH1A1ALDH3A1
SCHEMBL571882 0.80 CES1 (0.71) CES1BCHETGM2ALDH1A1ALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585489-A2 AGENT FOR DYEING FIBRES CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2005-10-19 EP claimed
WO-2004058203-A2 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (US) 2004-07-15 WO claimed