Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253406 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPK1TP53 | |
| SCHEMBL6254506 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPK1TP53 | |
| SCHEMBL6258504 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPK1TP53 | |
| SCHEMBL6256678 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPK1TP53 | |
| SCHEMBL6252806 | 0.82 | KMT2A (0.59) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL8167292 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPK1TP53 | |
| SCHEMBL6253456 | 0.81 | CYP11B1 (0.40) | ALDH1A1KDM4EHPGDMAPK1TP53 | |
| SCHEMBL16189447 | 0.79 | DHODH (0.37) | KDM4EMAPK1TP53SMN1; SMN2TDP1 | |
| SCHEMBL17532899 | 0.77 | CCR1 (0.52) | ALDH1A1KDM4EHPGDTSHRNFKB1 | |
| SCHEMBL14198210 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |