Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 1.00 |
| ▸ | C1R | P00736 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225135 | 0.86 | ELANE (1.00) | ELANEC1RMEN1KMT2A | |
| SCHEMBL9221774 | 0.83 | ELANE (1.00) | ELANEC1RMEN1KMT2A | |
| SCHEMBL5928801 | 0.82 | ELANE (1.00) | ELANE | |
| SCHEMBL7439329 | 0.77 | ELANE (0.68) | ELANEC1R | |
| SCHEMBL27151726 | 0.77 | ELANE (1.00) | ELANEC1RMEN1KMT2A | |
| SCHEMBL8070380 | 0.77 | ELANE (0.62) | ELANEC1R | |
| SCHEMBL272287 | 0.75 | ELANE (0.81) | ELANEC1RMEN1KMT2A | |
| SCHEMBL11023095 | 0.75 | ELANE (0.64) | ELANEC1RMEN1KMT2A | |
| SCHEMBL11817024 | 0.74 | ELANE (0.71) | ELANEC1RMEN1KMT2A | |
| SCHEMBL11814947 | 0.74 | C1R (1.00) | ELANEC1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265444-A | Nematicidal compounds, process for their preparation and their use | 华东理工大学 | 2023-06-20 | — | — | CN | disclosed |
| US-7339057-B2 | Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and carboxylic acid in the presence of a sulfonyl chloride and pyridine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| WO-2005018532-A2 | PURINE RECEPTOR BINDING COMPOUNDS | ACTAR AB (SE) | 2005-03-03 | — | — | WO | disclosed |
| US-6150372-A | IMMUNOINFLAMMATORY AND AUTOIMMUNE DISEASES; BLOCKING INTRACELLULAR SIGNAL TRANSDUCTION AND ACTIVATION OF TRANSCRIPTION FACTORS; KINASE INHIBITORS; ANTIARTHRITIC, ISCHEMIC AGENTS, MULTIPLE SCLEROSIS, TRANSPLANT REJECTION | SIGNAL PHARMACEUTICALS, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-5939421-A | TREATMENT OF IMMUNOINFLAMMATORY AND AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS, TRANSPLANT REJECTION; INHIBIT KINASE(S) THAT REGULATE ACTIVATION OF TRANSCRIPTION FACTORS TO PREVENT PRODUCTION OF INFLAMMATORY PROTEINS | SIGNAL PHARMACEUTICALS, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1999001441-A1 | QUINAZOLINE ANALOGS AND RELATED COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS | SIGNAL PHARMACEUTICALS, INC. (US) | 1999-01-14 | — | — | WO | disclosed |
| EP-0572782-B1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5444042-A | Administering peptide ketoamides, peptide ketoacids, and peptide ketoesters | CORTEX PHARMACEUTICALS (US) | 1995-08-22 | — | — | US | disclosed |
| US-5354755-A | Agricultural uses | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5276038-A | 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0564552-A1 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF NEURODEGENERATION | CORTEX PHARMACEUTICALS, INC. (US) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011850-A2 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF NEURODEGENERATION | CORTEX PHARMACEUTICALS, INC. (US) | 1992-07-23 | — | — | WO | disclosed |
| EP-0249858-B1 | FLUORALKYLSUBSTITUTED QUINOLINE DERIVATIVES, THEIR SYNTHESIS AND USE AGAINST UNWANTED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | disclosed |
| US-4847202-A | Heterocyclic inhibitors of serine proteases | GEORGIA TECH RESEARCH INSTITUTE (US) | 1989-07-11 | — | — | US | disclosed |
| US-4804404-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0249858-A2 | Fluoralkylsubstituted quinoline derivatives, their synthesis and use against unwanted plant growth | BASF Aktiengesellschaft (DE) | 1987-12-23 | — | — | EP | disclosed |
| US-4665070-A | SERINE PROTEINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0206323-A1 | 2-Oxy-4H-3,1-benzoxazin-4-one derivatives and related compounds | SYNTEX (U.S.A.) INC. (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4585793-A | Thioester inhibitors of serine proteases | GEORGIA TECH RESEARCH INSTITUTE (US) | 1986-04-29 | — | — | US | disclosed |