SCHEMBL272287

SCHEMBL272287

O=c1oc(-c2nc3ccccc3c(=O)o2)nc2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.81
C1R P00736 7/20 0.69
ALDH1A1 P00352 5/20 0.69
F2 P00734 4/20 0.69
KDM4E B2RXH2 4/20 0.69
KMT2A Q03164 4/20 0.69
NPC1 O15118 3/20 0.69
RAB9A P51151 3/20 0.69
HPGD P15428 3/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
NPSR1 Q6W5P4 1/20 0.69
PLG P00747 1/20 0.69
KLK1 P06870 1/20 0.69
PRSS1 P07477 1/20 0.69
C1S P09871 1/20 0.69
ATM Q13315 1/20 0.69
RXFP1 Q9HBX9 1/20 0.69
SMN1; SMN2 Q16637 3/20 0.67
MEN1 O00255 3/20 0.67
POLB P06746 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700941 0.92 ELANE (0.71) ELANEC1RALDH1A1F2KDM4E
SCHEMBL272702 0.90 ELANE (1.00) ELANEC1RALDH1A1F2KDM4E
SCHEMBL29456973 0.90 ELANE (0.93) ELANEC1RALDH1A1F2KDM4E
SCHEMBL125184 0.90 ELANE (0.93) ELANEC1RALDH1A1F2KDM4E
SCHEMBL9475884 0.90 C1R (0.78) ELANEC1RALDH1A1F2KDM4E
SCHEMBL29382161 0.90 ELANE (1.00) ELANEC1RALDH1A1F2KDM4E
SCHEMBL30914649 0.90 ELANE (0.73) ELANEC1RALDH1A1F2KDM4E
SCHEMBL29791056 0.90 C1R (0.78) ELANEC1RALDH1A1F2KDM4E
SCHEMBL2537274 0.90 ELANE (0.73) ELANEC1RALDH1A1F2KDM4E
SCHEMBL18963257 0.88 C1R (0.76) ELANEC1RALDH1A1F2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363506-A1 COMPOSITIONS AND METHODS FOR PROTECTING COATINGS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT Cytec Industries Inc. (US) 2024-05-08 EP claimed
EP-4251689-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM DISCOLORATION DUE TO EXPOSURE TO UV-C LIGHT Cytec Industries, Inc. (US) 2023-10-04 EP claimed
EP-4251690-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM THE DELETERIOUS EFFECTS EXPOSURE TO UV-C LIGHT Cytec Industries Inc. (US) 2023-10-04 EP claimed
WO-2023278282-A1 COMPOSITIONS AND METHODS FOR PROTECTING COATINGS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2023-01-05 WO claimed
US-20220411646-A1 COMPOSITIONS AND METHODS FOR PROTECTING COATINGS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-12-29 US claimed
US-20220169829-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-06-02 US claimed
WO-2022115573-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM DISCOLORATION DUE TO EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-06-02 WO claimed
WO-2022115578-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM THE DELETERIOUS EFFECTS EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-06-02 WO claimed
US-20220169828-A1 COMPOSITIONS AND METHODS FOR PROTECTING ORGANIC POLYMERIC MATERIALS FROM DISCOLORATION DUE TO EXPOSURE TO UV-C LIGHT CYTEC INDUSTRIES INC. (US) 2022-06-02 US claimed
US-20210403690-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING POLYMERIC ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2021-12-30 US claimed
US-20040219390-A1 Benzoxazinone and quinazolinone derivatives HONEYWELL INTERNATIONAL, INC. (US) 2004-11-04 US claimed
WO-2004066315-A2 BENZOXAZINONE AND QUINAZOLINONE DERIVATIVES HONEYWELL INTERNATIONAL INC. (US) 2004-08-05 WO claimed
US-20040132228-A1 Method and system for fabricating an OLED HONEYWELL INTERNATIONAL INC. (US) 2004-07-08 US claimed
EP-1054031-A2 Increasing the molecular weight and modification of condensation polymers Ciba SC Holding AG (CH) 2000-11-22 EP claimed
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP claimed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US claimed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP claimed
EP-0019061-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS TEIJIN LIMITED (JP) 1984-08-08 EP claimed
US-4291152-A CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE TEIJIN LIMITED (JP) 1981-09-22 US claimed
EP-0019061-A1 Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters TEIJIN LIMITED (JP) 1980-11-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040219390-A1 Benzoxazinone and quinazolinone derivatives XDH, AOX1, CYP4X1 ELANE 3064/4885C1R 4350/4885ALDH1A1 561/4885
US-20220411646-A1 COMPOSITIONS AND METHODS FOR PROTECTING COATINGS FROM THE DELETERIOUS EFFECTS OF EXPOSURE TO UV-C LIGHT ERCC1, ERCC5, AAAS ELANE 2046/4885C1R 128/4885ALDH1A1 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.