Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779214 | 0.81 | HSD11B1 (0.33) | BRS3RARBHSD11B1BCHEACHE | |
| Hydrochloric Acid SCHEMBL27464018 | 0.80 | HSD11B1 (0.32) | BRS3RARBAGTR1AGTR2HSD11B1 | |
| SCHEMBL7037024 | 0.79 | HSD11B1 (0.34) | BRS3RARBHSD11B1S1PR1 | |
| SCHEMBL7109568 | 0.78 | TLR8 (0.31) | RARBHSD11B1 | |
| SCHEMBL27757807 | 0.77 | HSD11B1 (0.36) | BRS3RARBLTB4R2HSD11B1 | |
| SCHEMBL27757730 | 0.76 | HSD17B10 (0.35) | RARBHSD11B1ACHE | |
| Hydrochloric Acid SCHEMBL6229400 | 0.76 | HSD11B1 (0.30) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL6886411 | 0.76 | NISCH (0.32) | — | |
| Hydrochloric Acid SCHEMBL6886430 | 0.76 | NISCH (0.32) | — | |
| SCHEMBL7182589 | 0.76 | RARB (0.32) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |