Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.54 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233041 | 0.84 | FYN (0.62) | FYNKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL3227740 | 0.79 | KMO (0.56) | MEN1KMT2ANPC1 | |
| SCHEMBL505220 | 0.78 | RXFP1 (0.69) | L3MBTL1MEN1KMT2AMAPTMPO | |
| SCHEMBL30022965 | 0.78 | RXFP1 (0.69) | L3MBTL1MEN1KMT2AMAPTMPO | |
| SCHEMBL19706639 | 0.76 | PIK3C3 (0.58) | MAPK14TOP2AKIF11 | |
| SCHEMBL25585874 | 0.75 | TOP2A (0.48) | FYNKITKDRMAPK14TOP2A | |
| SCHEMBL10248025 | 0.74 | MAPT (0.64) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL3247981 | 0.74 | PTGS1 (0.61) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL3246389 | 0.73 | CTSC (0.58) | FYNKITKDRMAPK14MEN1 | |
| SCHEMBL40311 | 0.73 | TSHR (0.53) | ABCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |