SCHEMBL6259239

SCHEMBL6259239

CC=C(N)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.48
RECQL P46063 2/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
POLB P06746 2/20 0.48
CYP2C19 P33261 2/20 0.48
F2 P00734 1/20 0.48
F10 P00742 1/20 0.48
F12 P00748 1/20 0.48
F7 P08709 1/20 0.48
F3 P13726 1/20 0.48
PKM P14618 1/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
MAPT P10636 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KMT2A Q03164 2/20 0.44
PRSS1 P07477 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10669214 1.00 BLM (0.48) BLMRECQLTSHRTDP1POLB
SCHEMBL19159184 0.80 TDP1 (0.41) BLMRECQLTSHRTDP1POLB
SCHEMBL6662244 0.79 BLM (0.44) BLMRECQLTSHRTDP1POLB
SCHEMBL15046255 0.79 BLM (0.44) BLMRECQLTSHRTDP1POLB
SCHEMBL2396375 0.78 BLM (0.48) BLMRECQLTSHRTDP1POLB
SCHEMBL12449790 0.78 BLM (0.48) BLMRECQLTSHRTDP1POLB
SCHEMBL17253723 0.78 BLM (0.48) BLMRECQLTSHRTDP1POLB
SCHEMBL3471389 0.78 BLM (0.48) BLMRECQLTSHRTDP1POLB
SCHEMBL16432782 0.78 BLM (0.48) BLMRECQLTSHRTDP1POLB
SCHEMBL15434763 0.77 CYP3A4 (0.42) BLMRECQLTSHRTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020029846-A1 RAPID SYNTHESIS METHOD FOR BIOMASS-BASED AMINE COMPOUND 南京农业大学 2020-02-13 WO claimed
WO-2020029846-A1 RAPID SYNTHESIS METHOD FOR BIOMASS-BASED AMINE COMPOUND 南京农业大学 2020-02-13 WO disclosed
US-10385013-B2 Micro/nano materials, products obtained by covalently modifying surface of micro/nano materials with hydrophilic materials, and method for making same CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) 2019-08-20 US disclosed
EP-3470443-A1 MICRO/NANOMATERIAL, PRODUCT THEREOF WITH SURFACE COVALENTLY MODIFIED WITH HYDROPHILIC MATERIAL, AND MANUFACTURING METHOD Chongqing Bolanying (BLY) Biotechnology Co., Ltd., China (CN) 2019-04-17 EP disclosed
US-20190077746-A1 MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) 2019-03-14 US disclosed
WO-2005058330-A1 PHOSPHORUS CONTAINING COMPOUNDS USEFUL FOR THE REGULATION OF LDL AND LP(A) LEVELS QUATRX PHARMACEUTICALS CO. (US) 2005-06-30 WO disclosed
WO-2003106399-A2 PROCESS FOR PREPARING N-PROTECTED β-AMINO ALDEHYDE COMPOUNDS THERAVANCE, INC. (US) 2003-12-24 WO disclosed
US-4755599-A 3-phenyl-2-propeneamine derivatives, their preparation and composition containing them RHONE-POULENC SANTE (FR) 1988-07-05 US disclosed
US-4686309-A ANTIDEPRESSANTS RHONE-POULENC SANTE (FR) 1987-08-11 US disclosed
US-4104383-A PSYCHOSTIMULANT, ANTISPASMODIC, HYPOTENSIVE, ANALGESIC C M INDUSTRIES (FR) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077746-A1 MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME PHOSPHO1, PTMS, PAM BLM 3573/4885RECQL 4225/4885TSHR 2276/4885
US-10385013-B2 Micro/nano materials, products obtained by covalently modifying surface of micro/nano materials with hydrophilic materials, and method for making same PHOSPHO1, PTMS, PAM BLM 3573/4885RECQL 4225/4885TSHR 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.