Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6414121 | 0.99 | CCKAR (0.54) | CCKARKMT2ATSHRMAPTLMNA | |
| SCHEMBL6260535 | 0.91 | KMT2A (0.52) | CCKARKMT2ATSHRMAPTLMNA | |
| Hydrochloric Acid SCHEMBL6414463 | 0.91 | KMT2A (0.54) | CCKARKMT2ATSHRMAPTLMNA | |
| Hydrochloric Acid SCHEMBL6421176 | 0.90 | KMT2A (0.52) | CCKARKMT2ATSHRMAPTLMNA | |
| SCHEMBL6263633 | 0.90 | KMT2A (0.53) | CCKARKMT2ATSHRMAPTLMNA | |
| SCHEMBL6265999 | 0.86 | KMT2A (0.56) | CCKARKMT2ATSHRMAPTLMNA | |
| SCHEMBL6415048 | 0.86 | KMT2A (0.62) | KMT2ATSHRMAPTLMNAALDH1A1 | |
| SCHEMBL6416255 | 0.85 | TSHR (0.65) | KMT2ATSHRMAPTLMNAALDH1A1 | |
| SCHEMBL6259498 | 0.85 | KMT2A (0.55) | CCKARKMT2ATSHRMAPTLMNA | |
| SCHEMBL6415443 | 0.85 | TSHR (0.59) | KMT2ATSHRMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590329-A1 | N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | Aventis Pharma S.A. (FR) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004078732-A1 | N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2004-09-16 | — | — | WO | disclosed |