Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418198 | 0.87 | TSHR (0.60) | KMT2ATSHRGAALMNAMAPK1 | |
| SCHEMBL6419968 | 0.87 | TSHR (0.50) | KMT2ATSHRGAALMNAMAPK1 | |
| SCHEMBL6261073 | 0.86 | TSHR (0.56) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL6263738 | 0.86 | TSHR (0.56) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL6259250 | 0.86 | CCKAR (0.55) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6414121 | 0.85 | CCKAR (0.54) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL6416255 | 0.84 | TSHR (0.65) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL6261963 | 0.84 | TSHR (0.53) | KMT2ATSHRGAALMNAMAPK1 | |
| SCHEMBL6415443 | 0.83 | TSHR (0.59) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL6261742 | 0.82 | TSHR (0.58) | KMT2ATSHRLMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | KMT2A 1284/4885TSHR 4236/4885GAA 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.