Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899166 | 0.94 | TSHR (0.40) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6261546 | 0.92 | MEN1 (0.40) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6258683 | 0.90 | TSHR (0.40) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL3037397 | 0.90 | MEN1 (0.41) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6255394 | 0.86 | TSHR (0.41) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9750723 | 0.85 | MEN1 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9750836 | 0.83 | MEN1 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6255557 | 0.81 | TSHR (0.41) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9750894 | 0.79 | TSHR (0.35) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL31544460 | 0.78 | MEN1 (0.41) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068410-A1 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | claimed |
| WO-2005068410-A1 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | disclosed |