Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614291 | 0.93 | TSHR (0.36) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL9750723 | 0.92 | MEN1 (0.34) | TSHRHRH3MEN1THRBHTT | |
| SCHEMBL13195976 | 0.90 | ALDH1A1 (0.36) | TSHRHRH3 | |
| SCHEMBL9750836 | 0.90 | MEN1 (0.38) | TSHRHRH3MEN1THRBHTT | |
| SCHEMBL18737001 | 0.89 | — | — | |
| SCHEMBL12254995 | 0.89 | CYP3A4 (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL6899166 | 0.85 | TSHR (0.40) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL22268711 | 0.85 | MEN1 (0.32) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL22268771 | 0.83 | CES2 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9750693 | 0.82 | TSHR (0.33) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284005-B1 | METHOD OF PRODUCTION OF POLYOLEFINS | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| US-4981930-A | POLYMERIZATION CATALYSTS | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0284005-A2 | Method of production of polyolefins | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |