Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004460 | 0.80 | MAPT (0.50) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL27560495 | 0.77 | MAPT (0.52) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL632551 | 0.75 | TDP1 (0.56) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL31174454 | 0.75 | TDP1 (0.56) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL6261147 | 0.72 | CYP1A2 (0.42) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL10996019 | 0.72 | MAPT (0.50) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL27851104 | 0.71 | MAPT (0.50) | HSD17B10MAPTCYP1A2NPSR1CYP3A4 | |
| SCHEMBL29588182 | 0.70 | NPSR1 (0.53) | HSD17B10MAPTNPSR1GAASMN1; SMN2 | |
| SCHEMBL4431825 | 0.70 | NPSR1 (0.53) | HSD17B10MAPTNPSR1GAASMN1; SMN2 | |
| SCHEMBL4431827 | 0.70 | NPSR1 (0.53) | HSD17B10MAPTNPSR1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080319-A1 | HYDRAZINO ALCOHOL DERIVATIVES USEFUL AS INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-01 | — | — | WO | disclosed |