Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259389 | 0.89 | HDAC3 (0.32) | HDAC3HDAC6 | |
| SCHEMBL6262125 | 0.88 | HDAC3 (0.32) | HDAC3HDAC6SMN1; SMN2 | |
| SCHEMBL6263260 | 0.85 | VDR (0.33) | HDAC3HDAC6 | |
| SCHEMBL6258511 | 0.85 | HDAC6 (0.43) | HDAC3HDAC6 | |
| SCHEMBL6259393 | 0.81 | HDAC3 (0.34) | HDAC3HDAC6NPC1HTTRAB9A | |
| SCHEMBL6258662 | 0.77 | HDAC3 (0.30) | HDAC3HDAC6 | |
| SCHEMBL6265176 | 0.77 | HDAC3 (0.42) | HDAC3HDAC6RAB9A | |
| SCHEMBL3393336 | 0.77 | HDAC3 (0.54) | HDAC3HDAC6 | |
| SCHEMBL6265207 | 0.76 | HDAC6 (0.43) | HDAC3HDAC6 | |
| SCHEMBL6258571 | 0.75 | HDAC6 (0.43) | HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587905-A3 | VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1587905-A2 | VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004063348-A2 | VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |