Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264851 | 1.00 | LMNA (0.51) | LMNAHRH3EGFRDRD2KDM4E | |
| SCHEMBL6260328 | 1.00 | LMNA (0.51) | LMNAHRH3EGFRDRD2KDM4E | |
| Hydrochloric Acid SCHEMBL6139307 | 0.99 | LMNA (0.50) | LMNAHRH3EGFRDRD2KDM4E | |
| Hydrochloric Acid SCHEMBL6139551 | 0.99 | LMNA (0.50) | LMNAHRH3EGFRDRD2KDM4E | |
| Hydrochloric Acid SCHEMBL6140018 | 0.99 | LMNA (0.50) | LMNAHRH3EGFRDRD2KDM4E | |
| SCHEMBL6139799 | 0.76 | LMNA (0.60) | LMNAHRH3EGFRDRD2KDM4E | |
| SCHEMBL9610081 | 0.74 | LMNA (0.62) | LMNAHRH3EGFRDRD2KDM4E | |
| SCHEMBL22422293 | 0.72 | LMNA (0.96) | LMNAHRH3KDM4EALDH1A1GAA | |
| SCHEMBL18926546 | 0.71 | LMNA (1.00) | LMNAHRH3ALDH1A1GRIN1GRIN2B | |
| SCHEMBL29235526 | 0.70 | LMNA (0.60) | LMNAHRH3EGFRDRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196403-B1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI AVENTIS (FR) | 2005-11-09 | — | — | EP | disclosed |
| EP-1196403-A1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | Sanofi-Aventis (FR) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002380-A1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI-SYNTHELABO (FR) | 2001-01-11 | — | — | WO | disclosed |