⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661257 | 0.86 | — | — | |
| SCHEMBL25418582 | 0.85 | CA1 (0.35) | — | |
| SCHEMBL4652897 | 0.78 | — | — | |
| SCHEMBL9206399 | 0.78 | — | — | |
| SCHEMBL5729458 | 0.78 | — | — | |
| SCHEMBL23846298 | 0.77 | TDP1 (0.33) | — | |
| SCHEMBL12834041 | 0.76 | — | — | |
| SCHEMBL19485710 | 0.76 | TDP1 (0.32) | — | |
| SCHEMBL14681131 | 0.76 | CA1 (0.36) | — | |
| SCHEMBL9287028 | 0.75 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3713664-B1 | THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS | NOURYON CHEMICALS INT BV (NL) | 2022-01-05 | — | — | EP | claimed |
| EP-3678768-B1 | THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS | NOURYON CHEMICALS INT BV (NL) | 2021-07-14 | — | — | EP | claimed |
| EP-1470117-B1 | METHYLENELACTONE SYNTHESIS IN SUPERCRITICAL FLUIDS | DU PONT (US) | 2005-07-27 | — | — | EP | claimed |
| EP-0632023-B1 | Process for the preparation of gamma-vinylpyrrolidones | BASF AG (DE) | 1997-08-27 | — | — | EP | claimed |
| US-5496958-A | Preparation of 5-vinylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1996-03-05 | — | — | US | claimed |
| EP-0632023-A1 | Process for the preparation of gamma-vinylpyrrolidones | BASF Aktiengesellschaft (DE) | 1995-01-04 | — | — | EP | claimed |
| US-4740617-A | ACID CATLYSTS FOR HIGH SELECTIVITY | MONSANTO COMPANY (US) | 1988-04-26 | — | — | US | claimed |
| US-4564689-A | G-VINYL-G-BUTYROLACTONE FROM BUTADIENE AND ACETIC ACID, MANGANESE SALTS | MONSANTO COMPANY (US) | 1986-01-14 | — | — | US | claimed |
| US-4560775-A | REACTING BUTADIENE AND ACETIC ACID WITH A METAL SALT OXIDANT | MONSANTO COMPANY (US) | 1985-12-24 | — | — | US | claimed |
| EP-0078067-B1 | PROCESS FOR THE PREPARATION OF (OMEGA-CARBALKOXY-N-ALKYL) DIALKYL AMINES | ANIC S.p.A. (IT) | 1985-10-23 | — | — | EP | claimed |
| EP-0060365-B1 | PROCESS FOR PRODUCING GAMMA-VINYL-GAMMA BUTYROLACTONE | MONSANTO COMPANY (US) | 1985-08-07 | — | — | EP | claimed |
| US-4526990-A | Reacting butadiene and acetic acid in the presence of metal ion oxidants | MONSANTO COMPANY (US) | 1985-07-02 | — | — | US | claimed |
| US-4468522-A | Process for the preparation of (omega-carboalkoxy-nor.alkyl)-dialkylamines | ANIC S.P.A. (IT) | 1984-08-28 | — | — | US | claimed |
| US-4460787-A | COPPER OR SILVER COMPOUNDS | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | claimed |
| EP-0078067-A1 | Process for the preparation of (omega-carbalkoxy-n-alkyl) dialkyl amines | ANIC S.p.A. (IT) | 1983-05-04 | — | — | EP | claimed |
| US-4380650-A | Lactone process | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | claimed |
| EP-0060365-A2 | Process for producing gamma-vinyl-gamma butyrolactone | MONSANTO COMPANY (US) | 1982-09-22 | — | — | EP | claimed |
| US-4158741-A | CATALYSTIC DECYCLIZATION AND ISOMERIZATION OF GAMMA-VINYL-GAMMA-BUTYROLACTONE | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1979-06-19 | — | — | US | claimed |
| US-4022822-A | Process for preparing sorbic acid | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-05-10 | — | — | US | claimed |
| CN-105957722-A | ELECTRIC STORAGE DEVICE | 太阳诱电株式会社 | 2016-09-21 | — | — | CN | disclosed |
| CN-103228638-B | Conversion of 5- (chloromethyl) -2-furaldehyde to 5-methyl-2-furoic acid and derivatives thereof | INCITOR INC. (US) | 2016-01-20 | — | — | CN | disclosed |
| CN-105073705-A | Process for preparing succinic acid esters | JOHNSON MATTHEY DAVY TECHNOLOGIES LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-105050999-A | Process for the preparation of succinic acid ester | JOHNSON MATTHEY DAVY TECHNOLOGIES LTD | 2015-11-11 | — | — | CN | disclosed |
| US-9108940-B2 | Conversion of 5-(chloromethyl)-2-furaldehyde into 5-methyl-2-furoic acid and derivatives thereof | XF TECHNOLOGIES INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8822696-B2 | Ligand for asymmetric synthesis catalyst, and process for production of alpha-alkenyl cyclic compound using the same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20140194633-A1 | CONVERSION OF 5-(CHLOROMETHYL)-2-FURALDEHYDE INTO 5-METHYL-2-FUROIC ACID AND DERIVATIVES THEREOF | XF BIOSOLUTIONS, LLC | 2014-07-10 | — | — | US | disclosed |
| US-8710250-B2 | Conversion of 5-(chloromethyl)-2-furaldehyde into 5-methyl-2-furoic acid and derivatives thereof | XF TECHNOLOGIES INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130267719-A1 | CONVERSION OF 5-(CHLOROMETHYL)-2-FURALDEHYDE INTO 5-METHYL-2-FUROIC ACID AND DERIVATIVES THEREOF | XF BIOSOLUTIONS, LLC | 2013-10-10 | — | — | US | disclosed |
| CN-103333526-A | Silicon/germanium particle inks, doped particles, printing and processes for semiconductor applications | NANOGRAM CORP | 2013-10-02 | — | — | CN | disclosed |
| CN-102076740-B | Heat-resistant resin precursor and photosensitive resin composition using same | ASAHI KASEI E MATERIALS CORP | 2013-08-21 | — | — | CN | disclosed |
| CN-103228638-A | Conversion of 5- (chloromethyl) -2-furaldehyde to 5-methyl-2-furoic acid and derivatives thereof | INCITOR LLC | 2013-07-31 | — | — | CN | disclosed |
| US-20120220780-A1 | LIGAND FOR ASYMMETRIC SYNTHESIS CATALYST, AND PROCESS FOR PRODUCTION OF ALPHA-ALKENYL CYCLIC COMPOUND USING SAME | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |
| CN-102076740-A | Heat-resistant resin precursor and photosensitive resin composition using same | ASAHI KASEI E MATERIALS CORP | 2011-05-25 | — | — | CN | disclosed |
| CN-101842378-A | Phosphadiazine HCV polymerase inhibitors IV | IDENIX PHARMACEUTICALS INC (US) | 2010-09-22 | — | — | CN | disclosed |
| EP-1264818-A1 | A method for treating an effluent containing sorbic acid and/or a salt thereof and an effluent disposal device | Daicel Chemical Industries, Ltd. (JP) | 2002-12-11 | — | — | EP | disclosed |
| CN-1345316-A | Process for preparation of alpha-methylenelactones and alpha-substituted hydrocarbylidene lactones | DU PONT (US) | 2002-04-17 | — | — | CN | disclosed |
| US-20010011644-A1 | Method for treating an effluent containing sorbic acid and/or a salt thereof and an effluent disposal device | DAICEL CHEMICAL INDUSTRIES, LTD. | 2001-08-09 | — | — | US | disclosed |
| US-6214241-B1 | USING HYPOHALOGENOUS ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0924184-A2 | A method for treating an effluent containing sorbic acid and/or a salt thereof and an effluent disposal device | Daicel Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0602515-B1 | Process for the preparation of 5-membered heterocycles | BASF AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0632023-B1 | Process for the preparation of gamma-vinylpyrrolidones | BASF AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5496958-A | Preparation of 5-vinylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1996-03-05 | — | — | US | disclosed |
| US-5496958-A | Preparation of 5-vinylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0329932-B1 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments | MERRELL DOW PHARMA (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5453516-A | Furanones, pyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| EP-0632023-A1 | Process for the preparation of gamma-vinylpyrrolidones | BASF Aktiengesellschaft (DE) | 1995-01-04 | — | — | EP | disclosed |
| EP-0632023-A1 | Process for the preparation of gamma-vinylpyrrolidones | BASF Aktiengesellschaft (DE) | 1995-01-04 | — | — | EP | disclosed |
| EP-0266730-B1 | Esters of hexadydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds | MERRELL DOW PHARMA (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0602515-A1 | Process for the preparation of 5-membered heterocycles | BASF Aktiengesellschaft (DE) | 1994-06-22 | — | — | EP | disclosed |
| US-5011846-A | Medicament compositions derived from quinolizine and quinolizinone and methods of use thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-4906755-A | Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0330824-A1 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmias | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0330788-A1 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmia | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0329902-A1 | Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of psychosis | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0329904-A1 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0329903-A1 | Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of glaucoma | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0329932-A2 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments | MERRELL PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4740617-A | ACID CATLYSTS FOR HIGH SELECTIVITY | MONSANTO COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4736063-A | OXIDATION OF ACETIC ACID AND BUTADIENE TO FORM ACETOXYHEXENOIC ACIDS; PURIFICATION AND ACID CATALYST CONVERSION | MONSANTO COMPANY (US) | 1988-04-05 | — | — | US | disclosed |
| US-4672140-A | CHEMICAL INTERMEDIATE FOR SORBIC ACID | MONSANTO COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4564689-A | G-VINYL-G-BUTYROLACTONE FROM BUTADIENE AND ACETIC ACID, MANGANESE SALTS | MONSANTO COMPANY (US) | 1986-01-14 | — | — | US | disclosed |
| US-4564689-A | G-VINYL-G-BUTYROLACTONE FROM BUTADIENE AND ACETIC ACID, MANGANESE SALTS | MONSANTO COMPANY (US) | 1986-01-14 | — | — | US | disclosed |
| US-4560775-A | REACTING BUTADIENE AND ACETIC ACID WITH A METAL SALT OXIDANT | MONSANTO COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| US-4560775-A | REACTING BUTADIENE AND ACETIC ACID WITH A METAL SALT OXIDANT | MONSANTO COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0078067-B1 | PROCESS FOR THE PREPARATION OF (OMEGA-CARBALKOXY-N-ALKYL) DIALKYL AMINES | ANIC S.p.A. (IT) | 1985-10-23 | — | — | EP | disclosed |
| EP-0060365-B1 | PROCESS FOR PRODUCING GAMMA-VINYL-GAMMA BUTYROLACTONE | MONSANTO COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0060365-B1 | PROCESS FOR PRODUCING GAMMA-VINYL-GAMMA BUTYROLACTONE | MONSANTO COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4526990-A | Reacting butadiene and acetic acid in the presence of metal ion oxidants | MONSANTO COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| US-4526990-A | Reacting butadiene and acetic acid in the presence of metal ion oxidants | MONSANTO COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| US-4526990-A | Reacting butadiene and acetic acid in the presence of metal ion oxidants | MONSANTO COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| US-4506095-A | Production of linear alkenoic acids and esters | CELANESE CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |
| US-4468522-A | Process for the preparation of (omega-carboalkoxy-nor.alkyl)-dialkylamines | ANIC S.P.A. (IT) | 1984-08-28 | — | — | US | disclosed |
| US-4460787-A | COPPER OR SILVER COMPOUNDS | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4460787-A | COPPER OR SILVER COMPOUNDS | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4388321-A | USING FURANONES | MONSANTO COMPANY (US) | 1983-06-14 | — | — | US | disclosed |
| EP-0078067-A1 | Process for the preparation of (omega-carbalkoxy-n-alkyl) dialkyl amines | ANIC S.p.A. (IT) | 1983-05-04 | — | — | EP | disclosed |
| US-4380650-A | Lactone process | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4380650-A | Lactone process | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4356317-A | REACTION OF BUTADIENE AND ACETIC ACID WITH METAL SALT OXIDANTS | MONSANTO COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| EP-0060365-A2 | Process for producing gamma-vinyl-gamma butyrolactone | MONSANTO COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| EP-0060365-A2 | Process for producing gamma-vinyl-gamma butyrolactone | MONSANTO COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| EP-0055934-A2 | Acyloxy alkenoic acids and process therefor | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | disclosed |
| EP-0055936-A1 | Sorbic acid process | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | disclosed |
| US-4247467-A | Preparation of gamma-lactones | NATIONAL DISTILLERS AND CHEMICAL CORP. (US) | 1981-01-27 | — | — | US | disclosed |
| US-4237312-A | ACYCLIC CONJUGATED DIOLEFIN ESTRIFIED BY A CARBOXYLIC ACID IN A COPPER OR ANTIMONY COMPOUND CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4158741-A | CATALYSTIC DECYCLIZATION AND ISOMERIZATION OF GAMMA-VINYL-GAMMA-BUTYROLACTONE | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1979-06-19 | — | — | US | disclosed |
| US-4158741-A | CATALYSTIC DECYCLIZATION AND ISOMERIZATION OF GAMMA-VINYL-GAMMA-BUTYROLACTONE | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1979-06-19 | — | — | US | disclosed |
| US-4100362-A | UNSATURATED ESTERS FROM CONJUGATED DIENE | PHILLIPS PETROLEUM COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4022822-A | Process for preparing sorbic acid | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-05-10 | — | — | US | disclosed |
| US-4022822-A | Process for preparing sorbic acid | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-05-10 | — | — | US | disclosed |
| US-4022822-A | Process for preparing sorbic acid | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-05-10 | — | — | US | disclosed |