⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206399 | 1.00 | — | — | |
| SCHEMBL4652897 | 1.00 | — | — | |
| SCHEMBL6259490 | 0.78 | — | — | |
| SCHEMBL16308846 | 0.75 | CA1 (0.46) | — | |
| SCHEMBL544336 | 0.73 | CA1 (0.41) | — | |
| SCHEMBL12834041 | 0.73 | — | — | |
| SCHEMBL21958195 | 0.70 | CA1 (0.42) | — | |
| SCHEMBL3699292 | 0.70 | CA1 (0.38) | — | |
| SCHEMBL14681131 | 0.69 | CA1 (0.36) | — | |
| SCHEMBL30886695 | 0.68 | CYP1A2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082270-A1 | Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-06-27 | — | — | US | claimed |
| US-20230321107-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2023-10-12 | — | — | US | disclosed |
| CN-104170157-B | Metal-air battery based on aluminum | 亚利桑那董事会代表亚利桑那大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-104170157-A | Aluminum-based metal-air batteries | UNIV ARIZONA | 2014-11-26 | — | — | CN | disclosed |
| EP-1483271-B1 | HETEROCYCLIC AMIDE DERIVATIVES HAVING GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-22 | — | — | EP | disclosed |
| US-7138415-B2 | Indolamid derivatives which possess glycogenphosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2006-11-21 | — | — | US | disclosed |
| US-7122567-B2 | Heterocyclic amide derivatives having glycogen phosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2006-10-17 | — | — | US | disclosed |
| US-20050131052-A1 | Heterocyclic amide derivatives having glycogen phosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2005-06-16 | — | — | US | disclosed |
| US-20050107362-A1 | Indolamid derivatives which possess glycogenphosphorylase inhibitory activity | ASTRA ZENECA AB (SE) | 2005-05-19 | — | — | US | disclosed |
| EP-1483240-A1 | INDOLAMID DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | AstraZeneca AB (SE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |
| US-20020082270-A1 | Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-06-27 | — | — | US | disclosed |
| CN-1044237-C | 4,1-benzoxazep in derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0602515-B1 | Process for the preparation of 5-membered heterocycles | BASF AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0408034-B1 | 3-Substituted vinyl cephalosporin derivatives | EISAI CO LTD (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5453516-A | Furanones, pyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| EP-0602515-A1 | Process for the preparation of 5-membered heterocycles | BASF Aktiengesellschaft (DE) | 1994-06-22 | — | — | EP | disclosed |
| US-5151417-A | Antibiotics and bactericides | EISAI CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| CN-1048706-A | 3-substituted vinyl cephalosporin derivatives and preparation method thereof | EISAI CO LTD (JP) | 1991-01-23 | — | — | CN | disclosed |
| EP-0408034-A1 | 3-Substituted vinyl cephalosporin derivatives | Eisai Co., Ltd. (JP) | 1991-01-16 | — | — | EP | disclosed |