Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837473 | 0.90 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL5838773 | 0.89 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL5837157 | 0.89 | P2RX7 (0.58) | P2RX7IL1B | |
| SCHEMBL6277609 | 0.88 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL6259129 | 0.87 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL6259541 | 0.83 | P2RX7 (0.48) | P2RX7IL1B | |
| SCHEMBL6267685 | 0.83 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL5837221 | 0.83 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL6259544 | 0.82 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL5837080 | 0.82 | P2RX7 (0.59) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581507-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | Pfizer Products Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058731-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2004-07-15 | — | — | WO | disclosed |