Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262032 | 0.97 | S1PR1 (0.50) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6262598 | 0.97 | S1PR1 (0.50) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6257601 | 0.97 | S1PR1 (0.50) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6255736 | 0.93 | S1PR1 (0.53) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6262261 | 0.93 | S1PR1 (0.53) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6257443 | 0.93 | S1PR1 (0.53) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6260196 | 0.93 | S1PR1 (0.53) | S1PR1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL6255767 | 0.91 | ESR1 (0.43) | S1PR1ALDH1A1LMNACYP3A4S1PR4 | |
| SCHEMBL6256769 | 0.89 | ESR1 (0.43) | S1PR1ALDH1A1LMNACYP3A4S1PR4 | |
| SCHEMBL6260625 | 0.87 | ALDH1A1 (0.39) | S1PR1ALDH1A1LMNACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |