Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270491 | 0.94 | — | — | |
| SCHEMBL8313859 | 0.93 | — | — | |
| SCHEMBL6269204 | 0.92 | SCN9A (0.34) | SCN9A | |
| SCHEMBL6267682 | 0.88 | — | — | |
| SCHEMBL8432607 | 0.87 | SCN9A (0.32) | SCN9A | |
| SCHEMBL8313695 | 0.84 | KDM4E (0.34) | — | |
| SCHEMBL8313504 | 0.84 | — | — | |
| SCHEMBL8314217 | 0.84 | — | — | |
| SCHEMBL8313718 | 0.84 | — | — | |
| SCHEMBL8316738 | 0.84 | ABCC9 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995438-B1 | BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF PERIPHERAL VASCULAR DISEASE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2005-11-30 | — | — | EP | claimed |
| US-6248777-B1 | VASCULAR DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-06-19 | — | — | US | claimed |
| EP-0995438-A1 | REMEDIES FOR PERIPHERAL CIRCULATION DISTURBANCES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-04-26 | — | — | EP | claimed |
| JP-10306026-A | — | — | None | — | — | JP | disclosed |
| EP-0995438-B1 | BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF PERIPHERAL VASCULAR DISEASE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1004316-B1 | THERAPEUTICS FOR DIABETIC COMPLICATIONS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20030065189-A1 | Processes for producing 4-substituted benzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6455708-B1 | SUCH AS 2,2-BIS(FLUOROMETHYL)-N-(2-CYANOETHYL)-6-TRIFLUOROMETHYL-2H-1-BENZOPYRAN-4 -CARBOXAMIDE; USEFUL AS MEDICINES, AGRICHEMICALS AND COSMETICS, AND CHEMICAL INTERMEDIATES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-24 | — | — | US | disclosed |
| EP-1120412-A1 | PROCESSES FOR THE PREPARATION OF 4-SUBSTITUTED BENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-6248777-B1 | VASCULAR DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6218411-B1 | ADMINISTERING POTASSIUM CHANNEL ACTIVATOR FOR THERAPY OF DIABETIC COMPLICATION IN PATIENT SUFFERING FROM DIABETES MELLITUS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-1004316-A1 | REMEDIES FOR COMPLICATIONS OF DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-05-31 | — | — | EP | disclosed |
| EP-0995438-A1 | REMEDIES FOR PERIPHERAL CIRCULATION DISTURBANCES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0702952-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-12-08 | — | — | EP | disclosed |
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| JP-H10306026-A | THERAPEUTIC AGENT FOR DISTURBANCES OF PERIPHERAL CIRCULATION | CHUGAI PHARMACEUT CO LTD | 1998-11-17 | — | — | JP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5646310-A | HYPOTENSIVE AGENTS, POTASSIUM CHANNEL ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0702952-A1 | BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1996-03-27 | — | — | EP | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065189-A1 | Processes for producing 4-substituted benzopyran derivatives | CYP3A4, PARP14, BTD | SCN9A 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.