Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255767 | 0.80 | ESR1 (0.43) | THRBSPHK2SPHK1ALDH1A1 | |
| SCHEMBL6257443 | 0.76 | S1PR1 (0.53) | MEN1KMT2AALDH1A1USP2 | |
| Methyl Alcohol SCHEMBL19714946 | 0.63 | HTT (0.71) | HTTMEN1THRBKMT2AMAPT | |
| Methyl Alcohol SCHEMBL19714948 | 0.63 | HTT (0.71) | HTTMEN1THRBKMT2AMAPT | |
| Methylamine SCHEMBL19253096 | 0.63 | HTT (0.64) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL21828426 | 0.63 | THRB (0.70) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL21044729 | 0.63 | THRB (0.70) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL21044640 | 0.63 | THRB (0.70) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL21341773 | 0.63 | THRB (0.70) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL21044639 | 0.63 | THRB (0.70) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |