Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259805 | 1.00 | HTT (0.53) | HTTMEN1THRBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8499512 | 0.98 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8498337 | 0.98 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8498807 | 0.98 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10726291 | 0.89 | HTT (0.53) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL8498308 | 0.88 | TNNC1 (0.58) | MEN1KMT2ATNNC1S1PR1SGPL1 | |
| SCHEMBL1132557 | 0.88 | TNNC1 (0.58) | MEN1KMT2ATNNC1S1PR1SGPL1 | |
| SCHEMBL775505 | 0.88 | TNNC1 (0.58) | MEN1KMT2ATNNC1S1PR1SGPL1 | |
| SCHEMBL6256417 | 0.88 | TNNC1 (0.58) | MEN1KMT2ATNNC1S1PR1SGPL1 | |
| SCHEMBL1117911 | 0.88 | TNNC1 (0.58) | MEN1KMT2ATNNC1S1PR1SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |