Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.53 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625432 | 0.90 | PIK3CA (0.50) | PIK3CAHASPINKCNH2MAP3K12 | |
| SCHEMBL624967 | 0.87 | PIK3CA (0.55) | PIK3CAHASPINKCNH2FLT3MAP3K12 | |
| SCHEMBL626169 | 0.87 | MAP3K12 (0.41) | PIK3CAMAP3K12 | |
| SCHEMBL624411 | 0.85 | PIK3CA (0.54) | PIK3CAHASPINKCNH2FLT3KIT | |
| SCHEMBL625732 | 0.84 | PIK3CA (0.53) | PIK3CAKCNH2MAP3K12 | |
| SCHEMBL627410 | 0.82 | PIK3CA (0.57) | PIK3CAHASPINKCNH2FLT3KIT | |
| SCHEMBL626262 | 0.82 | PIK3CA (0.54) | PIK3CAHASPINKCNH2FLT3MAP3K12 | |
| SCHEMBL625620 | 0.81 | PIK3CA (0.56) | PIK3CAHASPINKCNH2FLT3KIT | |
| SCHEMBL625746 | 0.81 | PIK3CA (0.54) | PIK3CAHASPINKCNH2FLT3KIT | |
| SCHEMBL624869 | 0.81 | PIK3CA (0.52) | PIK3CAHASPINKCNH2MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |