Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765833 | 0.89 | ACHE (0.58) | ACHEMETAP1MTNR1AMTNR1BLMNA | |
| Ethylene SCHEMBL8765917 | 0.86 | ACHE (0.56) | ACHEMETAP1MTNR1AMTNR1BLMNA | |
| SCHEMBL605776 | 0.86 | ACHE (0.52) | ACHEMETAP1MTNR1AMTNR1BLMNA | |
| SCHEMBL8337714 | 0.82 | ACHE (0.65) | ACHEMETAP1CYP19A1MAPK14HTR2A | |
| SCHEMBL603907 | 0.79 | MAOB (0.48) | ACHEMTNR1AMTNR1BLMNACYP19A1 | |
| SCHEMBL603908 | 0.79 | MAOB (0.48) | ACHEMTNR1AMTNR1BLMNACYP19A1 | |
| SCHEMBL6881129 | 0.78 | ACHE (0.63) | ACHEMETAP1GAACYP19A1HTR2A | |
| SCHEMBL10768744 | 0.78 | ACHE (0.58) | ACHEMETAP1MTNR1AMTNR1BCYP19A1 | |
| SCHEMBL31562781 | 0.77 | ACHE (0.61) | ACHEMETAP1GAA | |
| SCHEMBL385595 | 0.77 | ACHE (0.61) | ACHEMETAP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603481-A2 | AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | Abbott GmbH & Co. KG (DE) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020131-A2 | AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-02-16 | — | — | WO | disclosed |