SCHEMBL6262575

SCHEMBL6262575

Cc1sc(-c2ccccc2)nc1CCOc1ccc2cc(C(CP(=O)(O)O)P(=O)(O)O)[nH]c2c1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.47
PPARA Q07869 19/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238393 0.92 PPARG (0.42) PPARGPPARA
SCHEMBL6261797 0.86 PPARG (0.45) PPARGPPARA
SCHEMBL6245005 0.83 PPARG (0.52) PPARGPPARA
SCHEMBL6242609 0.79 PPARG (0.39) PPARGPPARA
SCHEMBL6242406 0.77 PPARG (0.43) PPARGPPARA
SCHEMBL6241216 0.76 PPARG (0.43) PPARGPPARA
SCHEMBL6243414 0.73 KMT2A (0.43) PPARGPPARA
SCHEMBL6244466 0.72 RARA (0.37) PPARGPPARA
SCHEMBL14142874 0.72 PPARA (0.57) PPARGPPARA
SCHEMBL6243281 0.72 PPARG (0.51) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005028488-A1 HETEROARYL PHOSPHINYL AND THIOPHOSPHINYL COMPOUNDS FOR REGULATION OF GLUCOSE, TRIGLYCERIDES, AND LDL/HDL LEVELS QUATRX PHARMACEUTICALS CO. (US) 2005-03-31 WO claimed