Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007134 | 0.85 | ACP3 (0.54) | CNR2TSHRALDH1A1ACP3P2RX7 | |
| SCHEMBL4189236 | 0.81 | CNR2 (0.49) | CNR2CNR1TSHRALDH1A1ACP3 | |
| SCHEMBL6260007 | 0.75 | TSHR (0.39) | CNR2CNR1TSHRALDH1A1HIF1A | |
| SCHEMBL20547735 | 0.71 | CNR2 (0.57) | CNR2CNR1ACP3P2RX7LMNA | |
| SCHEMBL30240014 | 0.71 | CNR2 (0.57) | CNR2CNR1ACP3P2RX7LMNA | |
| SCHEMBL4214299 | 0.71 | ACP3 (0.47) | CNR2ALDH1A1ACP3P2RX7L3MBTL1 | |
| SCHEMBL8429801 | 0.71 | P2RX7 (0.47) | CNR2ALDH1A1ACP3P2RX7L3MBTL1 | |
| SCHEMBL3535353 | 0.71 | TSHR (0.50) | CNR1TSHRALDH1A1HIF1AL3MBTL1 | |
| SCHEMBL4710744 | 0.70 | P2RX7 (0.40) | CNR2CNR1TSHRALDH1A1P2RX7 | |
| SCHEMBL29523337 | 0.70 | ACP3 (0.46) | CNR2TSHRALDH1A1ACP3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077463-A2 | LIGAND FOR A MONOAMINE RECEPTOR OR TRANSPORTER FOR TREATING ADDICTION OR DEPENDENCE | SEPRACOR INC. (US) | 2005-08-25 | — | — | WO | disclosed |