Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CD69 | Q07108 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263195 | 0.86 | PTPN1 (0.54) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL3906779 | 0.86 | PTPN1 (0.54) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL24496665 | 0.78 | KMT2A (0.68) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL11626866 | 0.75 | TDP1 (0.50) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL18095045 | 0.73 | KMT2A (1.00) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL3946663 | 0.72 | L3MBTL1 (0.50) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL6276054 | 0.72 | KDM4E (0.51) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL23018059 | 0.71 | KMT2A (0.68) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL6264816 | 0.70 | KMT2A (0.77) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL3280235 | 0.69 | KMT2A (0.76) | KMT2AMEN1CYP1A2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |