Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942110 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1GLAPGRADRA2A | |
| SCHEMBL7644507 | 0.81 | HCAR2 (0.41) | TSHRALDH1A1THRBTP53LMNA | |
| SCHEMBL10409301 | 0.80 | ALDH1A1 (0.43) | TSHRALDH1A1GLAPGRADRA2A | |
| SCHEMBL1900060 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1GLAPGRADRA2A | |
| SCHEMBL8975083 | 0.79 | TSHR (0.46) | TSHRALDH1A1GLAPGRADRA2A | |
| SCHEMBL14135507 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1GLATHRBTP53 | |
| SCHEMBL11653002 | 0.78 | TP53 (0.44) | TSHRALDH1A1GLAPGRADRA2A | |
| SCHEMBL14135329 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1GLAPGRADRA2A | |
| SCHEMBL11671701 | 0.77 | TDP1 (0.42) | TSHRALDH1A1GLATHRBPGR | |
| SCHEMBL8550442 | 0.75 | TP53 (0.38) | TSHRALDH1A1THRBPGRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016976-A2 | HEMOCOMPATIBLE POLYMER SYSTEMS AND RELATED METHODS | ALBRIGHT ROBERT L (US) | 2005-02-24 | — | — | WO | claimed |